منابع مشابه
Chromosome studies of solid tumours.
Introduction Cytogenetic analysis of malignant cells very often indicates acquired chromosome changes-that is, deviations from the normal constitutional 46,XX or 46,XY karyotype. Much of what we know about these changes is derived from studying leukaemias and lymphomas. Many of these abnormalities are nonrandom, and particular chromosome changes are consistently found in particular disease type...
متن کاملCHROMOSOME STUDIES OF IRANIAN MEMBERS OF TRIBE SOPHOREAE (FAMILY LEGUMINOSAE
The tribe Sophoreae sensu Polhill [9,10] is a large and diverse assemblage comprising the ancient and primitive ancestral stocks of Papilionoideae. The most frequent chromosome basic numbers in this tribe are x = 11 and x = 9 but chromosome numbers range from x = 8-14 are also known. In this study chromosome numbers and karyotype variation of Iranian members of tribe Sophoreae are reported. Ira...
متن کاملMultidrug resistance in solid tumours
Introduction: Most cancers show heterogeneity of response to chemotherapy. This may be due in part to the differential expression of drug resistance proteins and the molecular targets of the drugs concerned. Methods: An ex vivo ATP-based Tumour Chemosensitivity Assay (ATP-TCA), immunohistochemistry and quantitative RT-PCR have been used to assess the chemosensitivity and resistance of a variety...
متن کاملMetabolic scaling in solid tumours
Tumour metabolism is an outstanding topic of cancer research, as it determines the growth rate and the global activity of tumours. Recently, by combining the diffusion of oxygen, nutrients, and metabolites in the extracellular environment, and the internal motions that mix live and dead cells, we derived a growth law of solid tumours which is linked to parameters at the cellular level. Here we ...
متن کاملCytogenetic investigations of solid tumours of children.
The association of non-random chromosome abnormalities with solid tumours of childhood may improve accuracy of diagnosis and prognosis and lead to a better understanding of their biology. In a pilot study in the Northern region of England fresh tumour biopsy specimens were obtained from 39 to 72 consecutive solid tumours in children who presented over a period of 21 months. Cytogenetic analysis...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1992
ISSN: 0021-9746
DOI: 10.1136/jcp.45.7.556